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Comments for the paper: "Association of household cleaning agents and disinfectants with asthma in young German adults.", 2017, Occup Environ Med

Disinfectant sprays at home were associated with an increased risk of new-onset (incident) asthma in 19-24 year-old young people from Dresden and Munich (Odds Ratio 2.79, 95% CI 1.14-6.83). The risk for other sprays was less clear. there was no association between current asthma and cleaning spr ...

Published Paper Comments, , 6/1/2017, 6/1/2017,

Comments for the page titled: "Referral Centres"

What would be potential causative agents in a theatre environment? Patient is a theatre nurse, doesn't use latex

Page Comments, , 5/12/2017, 5/13/2017,

Comments for the paper: "Development of a job-task-exposure matrix to assess occupational exposure to disinfectants among US nurses", 2017, Occup Environ Med

This paper tries to estimate exposures to cleaning agents and biocides in nurses and finds that a job-exposure matrix is not very effective at this, but adding a section on tasks is better (a JTEM, job-task exposure matrix). Perhaps there is no real substitute for an occupational history? Expos ...

Published Paper Comments, , 2/10/2017, 5/1/2017,

Comments for the paper: "Military small arms fire in association with acute decrements in lung function", 2017, Occup Environ Med

Could this be due to tetrazine sensitisation from the detonator?

Published Paper Comments, , 4/30/2017, 4/30/2017,

Comments for the paper: "Can serum cytokine profile discriminate irritant-induced and allergen-induced symptoms? A cross-sectional study in workers mostly exposed to laboratory animals.", 2017, Occup

Studies of laboratory animal allergy have consistently shown a large number of workers with work-related asthma or rhinitis but negative IgE to rat and mouse allergens. The current study starts with the hypothesis that those with negative IgE have irritant responses to the animal allergens and c ...

Published Paper Comments, , 4/30/2017, 4/30/2017,

Comments for the paper: "Effect of anti-IgE in occupational asthma caused by exposure to low molecular weight agents.", 2017, Allergy

This is an interesting study showing that anti-IgE in the mouse reduces the effects of nasal challenge with persulphates in dermally sensitised mice. There is some controversy on the role of IgE antibodies in human persulphate asthma, but this study paves the way for a trial in man (or women).

Published Paper Comments, , 4/29/2017, 4/29/2017,

Comments for the paper: "Bagpipe lung; a new type of interstitial lung disease?", 2017, Thorax

This is an interesting case report of fatal HP in a bagpipe player, whose bagpipes yielded Penicillium species, Fusarium oxysporum, Rhodotorula mucilaginosa and Trichosporon mucoides. The diagnosis was made from a history of improvement while away from home and bagpipes for 3 months in Australia ...

Published Paper Comments, , 3/28/2017, 3/28/2017,

Needing some help with understanding this serial PEFR report

This person had an acute exposure to diesel exhaust fumes and now have persistent respiratory symptoms. All previous investigation inclusive of serial peak flow and methacholine challenge was negative. She is no longer exposed but is on asthma medication and reportedly quite symptomatic. I rep ...

Occupational Asthma, Health Professional, 3/6/2017, 3/8/2017,

Comments for the paper: "Cooking smoke and respiratory symptoms of restaurant workers in Thailand", 2017, BMC Pulmonary Medicine

There is interesting data in this study, but the messages are difficult to disentangle. The study includes 4 different types of restaurants and neighborhood controls. Some fry (Thai cuisine, going oil exposure), some boil noodles (in water(, some serve food cooked elsewhere (reheating only) and ...

Published Paper Comments, , 3/2/2017, 3/2/2017,

Comments for the paper: "Original article: The effects of growing up on a farm on adult lung function and allergic phenotypes: an international population-based study", 2017, Thorax

This extends the work on early life farm exposure and other measures of microbial biodiversity to adults, showing a continued protective effect on the reduction of atopy. Biodiversity was scored by schooling or play schooling under 5, early life dog in the home, sharing bedrooms and having older ...

Published Paper Comments, , 2/27/2017, 2/27/2017,