Oasys and Occupational Asthma

This website contains information on Occupational Asthma and a free multi award winning computer program called OASYS, which is used to help diagnose Occupational Asthma from serial peak flow records. Oasys shows further information and downloads for the Oasys program. References is a searchable database of more than 5000 published papers in the field of occupational asthma. Causes shows some of the causes of occupational asthma. The Shield scheme reports some statistics for occupational asthma, mainly in the West midlands region, UK. BOHRF shows the evidence based occupational asthma guidelines for the UK. The interactive Case Histories are a learning resource for interested health professionals. There are also Medics, Specialists, Employers and Worker sections.

Latest News

Occupational asthma: Biological monitoring in platinum refiners has very long half life Biological monitoring in platinum refiners has very long half life 04 06 2018
Occupational asthma: First cross-sectional study of 3D printers showing asthma, rhinitis and skin symptoms First cross-sectional study of 3D printers showing asthma, rhinitis and skin symptoms 04 06 2018
Occupational asthma: Oasys plots and challenge tests show concordant results Oasys plots and challenge tests show concordant results 19 05 2018
Occupational asthma: Enzyme allergy with negative IgE to native enzyme caused by genetic modification Enzyme allergy with negative IgE to native enzyme caused by genetic modification 09 04 2018
Occupational asthma: New highly potent sensitiser for plant husbandry New highly potent sensitiser for plant husbandry 04 04 2018

Latest Publications

Full Text Available for Evaluation of bronchodilator response in patients with airway obstruction QUADRELLI SA, RONCORONI AJ, MONTIEL GC, Evaluation of bronchodilator response in patients with airway obstruction , Respir Med, 1999;93:930-936,

Abstract Available for Acute Bronchodilator Response Has Limited Value in Differentiating Bronchial Asthma from COPD Chhabra SK, Acute Bronchodilator Response Has Limited Value in Differentiating Bronchial Asthma from COPD, J Asthma, 2009;42:367-372,

No Abstract Available for Differences in sensitivity, maximal response and position of the concentration-response curve to methacholine between asthmatics, patients with allergic rhinitis and healthy subjects Prieto L, Gutierrez V, Morales C, Marin J, Differences in sensitivity, maximal response and position of the concentration-response curve to methacholine between asthmatics, patients with allergic rhinitis and healthy subjects , Respir Med, 1998;92:88-94,

Go to "References" section.

Latest Forum Questions

1. Is it possible to have undiagnosed asthma if you have confirmed allergies and some family history and 2. Do you think that I could be allergic to bitrex?
I left school and went to work as a Pharmacology Laboratory Technician for over 2O years. I started work in 1987 when processes and procedures were not as good in this area as they are nowadays. My mother and brother are both asthmatics and I knew that I suffered from "hay fever" in the summer with runny eyes and sneezing. (Though I don't seem to have hay fever nowadays!). I have never been diagnosed with asthma, but after some time working (I really can't remember when this would have been now), I began to suspect that I was becoming allergic to animals at my work and via my GP, it was confirmed with skin prick tests that I was allergic to almost, if not all the animal species that I came into contact with. I was able to manage this reasonably well with various control measures (batter powered full face hood, nitrile gloves, annual lung function tests etc.) and as processes improved over the years, I didn't suffer too much because of it. I changed jobs four years ago and am now mainly office based. However, recently I experienced what I consider to be a delayed hypersensitive allergic/irritant skin reaction (urticaria) approximately 48hrs after a training session to be a qualitative face-fit tester. I believe that I may be one of the very few numbers of people that may be hypersensitive to bitrex (denatonium benzoate). There is so little research in this area, but there are sporadic reports of adverse respiratory and skin reactions in primarily the healthcare sector. Given my family history, my known allergies to animals and my known exposure to a fairly large number of substances over the years (including related bitrex-like subtances of local anesthetics such as lignocaine, xylocaine, procaine), could anyone give me their thoughts on my questions above and how I convince my OH Dept. that I think I do warrant an allergy text to this substance, to rule it in or out one way or another? Many thanks
Occupational Asthma, Worker, 1/31/2013, 7/18/2018,

Comments for the page titled: "Bird Fancier's Lung"
Comments for the page titled: "Bird Fancier's Lung"
Page Comments, , 5/8/2008, 6/13/2018,

Egg & peanut allergy greater predisposition to allergic alveolitis
My son is to start work in a centre for birds and animals. Birds include a few parakeets, pigeons, chickens. He has peanut allergy (can go into shock), and egg allergy (vomits violently). He is also allergic to shellfish, house dust and pollen. (Mild asthma -has inhalers). On the whole his allergies are controlled and don't rule his life or choices. I'm worried his existing sensitivities may be added to by bird bloom allergy. Is he more likely than the average person to develop issues over time. He is also considering adopting a parrot. He's never had exposure to birds. Would a skin prick test id an existing allergy, or would this only appear over time.
Oasys, Health Professional, 8/6/2016, 4/29/2018,

The Website

This website is run by the Oasys research group, part of the Midland Thoracic Society, UK. We are an independent group of clinicians and researchers, and run a clinical service for workers with occupational lung disease as part of the British National Health Service. We have developed the Oasys program to help ourselves and others in the diagnosis of occupational asthma. We have no specific funding, relying on research grants and the enthusiasm of our group. The website is written by Cedd Burge, who receives some funding from the group. The group meets about every 6 weeks on a Wednesday evening, as shown below.



As a casual user of this site (without logging in or registering) you can view all the information and use all the contact pages. Registered and logged in users (registering is free and we won't abuse your email) can download and use the Oasys program, ask and reply to questions in the forums, leave comments, add new references, add abstracts and full text links to existing references, answer questions in the case histories and provide evidence and suggest questions for future evidence based guidelines.

If you would like to be added to the list of known authors or collaborators then please register with the website (if you have not already done so) and then get in touch from the contact page. Once we have set the page up you will be able to edit it yourself and indicate which references you have written. Your picture will then be displayed along with each of these references. If you are already in these lists and would like to edit your page then please register with the website and then get in touch from the contact page.

Funding

Recent research grants / contracts have been received from the following.

The Oasys Team

Wasif Anees, Oasys Anees, Wasif (Oasys)
John Belcher, Oasys Belcher, John (Oasys)
Phil Bright, Oasys Bright, Phil (Oasys)
Cedd Burge, Oasys Burge, Cedd (Oasys)
Geraldine Burge, Birmingham Heartlands Hospital Burge, Geraldine (Birmingham Heartlands Hospital)
Sherwood Burge, Oasys Burge, Sherwood (Oasys)
Celia Catton, Oasys Catton, Celia (Oasys)
Vicki Drought, Oasys Drought, Vicki (Oasys)
Angela Evans, ARTP Evans, Angela (ARTP)
Paul Gannon, Dupont Gannon, Paul (Dupont)
John Jackson, Jackson Hocking Limited, UK Jackson, John (Jackson Hocking Limited, UK)
Sarah Manney, Birmingham Heartlands Hospital Manney, Sarah (Birmingham Heartlands Hospital)
Jennifer McCoach (now Croft), Oasys McCoach (now Croft), Jennifer (Oasys)
Emmet McGrath, Oasys McGrath, Emmet (Oasys)
David Miedinger, Lucern, Basel and Montreal Miedinger, David (Lucern, Basel and Montreal)
Vicky Moore, Oasys Moore, Vicky (Oasys)
Darren Newton, Oasys Newton, Darren (Oasys)
Charles Pantin, Keele, UK Pantin, Charles (Keele, UK)
Edward Parkes, Birmingham Heartlands Hospital Parkes, Edward (Birmingham Heartlands Hospital)
Alastair Robertson, Selly Oak Hospital Robertson, Alastair (Selly Oak Hospital)
Arun Dev Vellore, Oasys Vellore, Arun Dev (Oasys)
Gareth Walters, Heartlands Walters, Gareth (Heartlands)

Collaborators

Don Cockcroft, Saskatoon Cockcroft, Don (Saskatoon)
André Cartier, Hôpital de Sacré Coeur, Montreal, Quebec, Canada Cartier, André (Hôpital de Sacré Coeur, Montreal, Quebec, Canada)
Paul Cullinan, Royal Brompton Hospital, London, UK Cullinan, Paul (Royal Brompton Hospital, London, UK)
Jennifer Hoyle, North Manchester General Hospital Hoyle, Jennifer (North Manchester General Hospital)
Giana Moscato, Fondazione Salvatore Maugeri, Pavia Moscato, Giana (Fondazione Salvatore Maugeri, Pavia)
Olivier Vandenplas, Universite Mont-Goginne, Yvoir Vandenplas, Olivier (Universite Mont-Goginne, Yvoir)
Cecile Svanes, University of Bergen, Norway Svanes, Cecile (University of Bergen, Norway)
Hille Suojalehto, Finnish Institute of Occupational Health Suojalehto, Hille (Finnish Institute of Occupational Health)
Vivi Schlunssen, Aarhus Schlunssen, Vivi (Aarhus)
Jan-Paul Zock, Municipal Institute of Medical Research, Barcelona, Spain Zock, Jan-Paul (Municipal Institute of Medical Research, Barcelona, Spain)

Known Authors

J Leuppi, Basel Leuppi, J (Basel)
Maria Jesus Cruz, Barcelona Cruz, Maria Jesus (Barcelona)
David Bernstein, Cincinatti Bernstein, David (Cincinatti)
Catherine Lemière, Hôpital de Sacré Coeur, Montreal, Quebec, Canada Lemière, Catherine (Hôpital de Sacré Coeur, Montreal, Quebec, Canada)
Zana Lummus, Cincinatti Lummus, Zana (Cincinatti)
Xavier Munoz, Barcelona Munoz, Xavier (Barcelona)
Santiago Quirce, Madrid Quirce, Santiago (Madrid)
Susan Tarlo, Toronto Tarlo, Susan (Toronto)
Joaquin Sastre, Fundacion Jimenez Diaz, Madrid Sastre, Joaquin (Fundacion Jimenez Diaz, Madrid)
Rolf Merget, Bochum Merget, Rolf (Bochum)

Oasys and occupational asthma smoke logo