Paul Cullinan is collaborating on serial measuerments of PEF in biological enzyme detergent workers. Also collaborating with audit of occupational asthma services in the GORDS project. Further details on Paul Cullinan and his research can be found on his Imperial College homepage below. http://www1.imperial.ac.uk/medicine/people/p.cullinan/
Paul is involved with the following papers on occupational asthma.
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Nafees AA, Allana A, Kadir MM, Potts J, Minelli C, Semple S, Matteis SD, Burney P, Cullinan P,
A cluster randomised controlled trial to reduce respiratory effects of cotton dust exposure among textile workers – the MultiTex RCT study,
Eur Respir J,
2023;:,DOI: 10.1183/13993003.01028-2023
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Barber CM, Cullinan P, Feary J, Fishwick D, Hoyle J, Mainman H, Walters GI,
British Thoracic Society Clinical Statement on occupational asthma ,
Thorax,
2022;77:433-442,http:// dx. doi. org/ 10. 1136/ thoraxjnl- 2021- 218597
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Feary JR, Schofield SJ, Canizales J, Fitzgerald B, Potts J, Jones M, Cullinan P,
Laboratory animal allergy is preventable in modern research facilities,
Eur Respir J,
2019;53:1900171,10.1183/13993003.00171-2019
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De Matteis S, Jarvis D, Darnton A, Hutchings S, Sadhra S, Fishwick D, Rushton L, Cullinan P,
The occupations at increased risk of chronic obstructive pulmonary disease (COPD): analysis of lifetime job-histories in the population-based UK Biobank Cohort.,
Eur Respir J,
2019;:,DOI: 10.1183/13993003.00186-2019
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Brock Jacobsen I, Baelum J, Carstensen O, Skadhauge LR, Feary J, Cullinan P, Sherson DL.,
Delayed occupational asthma from epoxy exposure.,
Occup Med,
2019;69:511-514,10.1093/occmed/kqz088
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Suojalehto H, Suuronen K, Cullinan P, Lindström I, Sastre J, Walusiak-Skorupa J, Munoz X, Talini D, Klusackova P, Moore V, Merget R, Svanes C, Mason P, dell'Omo M, Moscato G, Quirce S, Hoyle J, Sherson D, Preisser A, Seed M, Rifflart C, Godet J, de Blay F, Vandenplas O, European network for the Phenotyping of Occupational Asthma (E-PHOCAS) investigators.,
Phenotyping occupational asthma caused by acrylates in a multicentre cohort study.,
J Allergy Clin Immunol Pract,
2019;:,10.1016/j.jaip.2019.10.017
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James PL, Cannon J, Barber CM, Crawford L, Hughes H, Jones M, Szram J, Cowman S, Cookson WOC, Moffatt MF, Cullinan P,
Metal worker’s lung: spatial association with Mycobacterium avium ,
Thorax,
2018;73:151-156,http://dx.doi.org/10.1136/thoraxjnl-2017-210226
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Vandenplas O, Godet J, Hurdubaea L, Rifflart C, Suojalehto H, Wiszniewska M, Munoz X, Sastre J, Klusackova P, Moore V, Merget R, Talini D, Svanes C, Mason P, dell'Omo M, Cullinan P, Moscato G, Quirce S, Hoyle J, Sherson D, Kauppi P, Preisser A, Meyer N, de Blay F, European network for the PHenotyping of OCcupational ASthma (E-PHOCAS) investigators.,
Are high- and low-molecular-weight sensitizing agents associated with different clinical phenotypes of occupational asthma?,
Allergy,
2018;74:261-272,https://doi.org/10.1111/all.13542
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Jones M, Blair S, MacNeill S, Welch J, Hole A, Baxter P, Cullinan P,
Occupational allergy to fruit flies (Drosophila melanogaster) in laboratory workers,
Occup Environ Med,
2017;74:422-425,http://dx.doi.org/10.1136/oemed-2016-103834
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Jones M, Welch J, Turvey J, Cannon J, Clark P, Szram J, Cullinan P,
Prevalence of sensitization to ‘improver’ enzymes in UK supermarket bakers,
Allergy,
2016;71:997-1000,10.1111/all.12854
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James PL, Cannon J, Crawford L, DSouza E, Barber C, Cowman S, Cookson WO, Moffatt MF, Cullinan P,
Molecular Detection of Mycobacterium Avium in Aerosolised Metal Working Fluid is Linked to a Localised Outbreak of Extrinsic Allergic Alveolitis in Factory Workers,
Am J Respir Crit Care Med,
2015;191:A2578,
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Jones, M., Schofield, S., Jeal, H., Cullinan, P.,
Respiratory protective equipment reduces occurrence of sensitization to laboratory animals,
Occup Med,
2014;64:104-108,
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Vandenplas O, Suojalehto H, Aasen T, Baur X, Burge PS, de Blay F, Fishwick D, Hoyle J, Maestrelli P, Muñoz X, Moscato G, Sastre J, Sigsgaard T, Suuronen K, Walusiak-Skorupa J, Cullinan P, the ERS Task Force on Specific Inhalation Challenges with Occupational Agents,
Specific inhalation challenge in the diagnosis of occupational asthma: consensus statement,
Eur Respir J,
2014;43:1573-1587,
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Moscato G, Pala G, Cullinan P, Folletti I, van Wijk G, Pignatti P, Quirce S,
EAACI Position Paper on assessment of cough in the workplace,
Allergy,
2014;69:292-304,
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Jones M, Jeal H, Schofield S, Harris JM, Shamji MH, Francis JN, Durham SR, Cullinan P,
Rat-specific IgG and IgG4 antibodies associated with inhibition of IgE–allergen complex binding in laboratory animal workers,
Occup Environ Med,
2014;71:619-623,10.1136/oemed-2014-102119
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Ghosh RE, Cullinan P, Fishwick D, Hoyle J, Warburton CJ, Strachan DP, Butland BK, Jarvis D,
Asthma and occupation in the 1958 birth cohort,
Thorax,
2013;68:365-371,
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Cullinan P, McGavin CR, Kreiss K, Nicholson AG, Maher TM, Howell T, Banks J, Newman Taylor AJ, Chen C-H, Tsai P-J, Shih T-S, Burge PS,
Obliterative bronchiolitis in fibreglass workers: a new occupational disease?,
Occup Environ Med,
2013;70:357-359,
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Fishwick D, Barber CM, Bradshaw LM, Ayres JG, Barraclough R, Burge S, Corne JM, Cullinan P, Frank TL, Hendrick D, Hoyle J, Curran AD, Niven R, Pickering T, Reid P, Robertson A, Stenton C, Warburton CJ, Nicholson PJ,
Standards of care for occupational asthma: an update
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Thorax,
2012;67:278-280,
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Brant A, Upchurch S, van Tongeren M, Zekveld C, Helm J, Barnes F, Newman Taylor AJ, Cullinan P,
Detergent protease exposure and respiratory disease: case-referent analysis of a retrospective cohort,
Occup Environ Med,
2009;66:754-758,
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Fishwick D, Barber CM, Bradshaw LM, Harris-Roberts J, Francis M, Naylor S, Ayres J, Burge PS, Corne JM, Cullinan P, Frank TL, Hendrick D, Hoyle J, Jaakkola M, Newman Taylor AJ, Nicholson P, Niven R,
Standards of care for occupational asthma,
Thorax,
2008;63:240-250,
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Jones MG, Floyd A, Nouri-Aria KT, Jacobson MR, Durham SR, Taylor AN, Cullinan P,
Is occupational asthma to diisocyanates a non-IgE-mediated disease?,
J Allergy Clin Immunol,
2007;119:757-758,
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Fishwick D, Bradshaw L, Henson M, Stenton C, Hendrick D, Burge PS, Niven R, Warburton C, Rogers T, Rawbone R, Cullinan P, Barber C, Pickering CAC, Williams N, Ayres JA, Curran AD,
Occupational asthma: an assessment of diagnostic agreement between physicians,
Occup Environ Med,
2007;64:185-190,
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McCreanor J, Cullinan P, Nieuwenhuijsen MJ, Stewart-Evans J, Malliarou E, Jarup L, Harrington R, Svartengren M, Han I-K, Ohman-Strickland P, Kian Fan Chung KF, Zhang J,
Respiratory Effects of Exposure to Diesel Traffic in Persons with Asthma,
N Engl J Med,
2007;357:2348--2358,10.1056/NEJMoa071535
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Brant A, Zekveld C, Welch J, Jones, M Newman Taylor AJ, Cullinan P,
The prognosis of occupational asthma due to detergent enzymes: clinical, immunological and employment outcomes,
J Allergy Clin Immunol,
2006;36:483-488,
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Nicholson PJ, Cullinan P, Newman Taylor AJ, Burge PS, Boyle C,
Evidence based guidelines for the prevention, identification, and management of occupational asthma,
Occup Environ Med,
2005;62:290-299,
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Brant A, Hole A, Cannon J, Helm J, Swales C, Welch J, Newman Taylor A, Cullinan P,
Occupational asthma caused by cellulase and lipase in the detergent industry,
Occup Environ Med,
2004;61:793-795,
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Nieuwenhuijsen MJ, Putcha V, Gordon S, Heederik D, Venables KM, Cullinan P, Newman Taylor AJ,
Exposure-response relationships among laboratory workers exposed to rats,
Occup Environ Med,
2002;60:104-108,
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Nightingale JA, Maggs R, Cullinan P, Donnelly LE, Rogers DF, Kinnersley R, Chung KF, Barnes PJ, Ashmore M, Newman-Taylor A,
Airway inflammation after controlled exposure to diesel exhaust particulates,
Am J Respir Crit Care Med,
2000;162:161-6,
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Cullinan P, Cook A, Gordon S, Nieuwenhuijsen MJ, Tee RD, Venables KM, McDonald JC, Newman Taylor AJ,
Allergen exposure, atopy and smoking as determinants of allergy to rats in a cohort of laboratory employees,
Eur Respir J,
1999;13:1139-1143,
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Cullinan P, Lowson D, Nieuwenhuijsen MJ, Gordon S, Tee RD, Venables KM, McDonald JC, Newman Taylor AJ,
Work related symptoms, sensitisation, and estimated exposure in workers not previously exposed to laboratory rats,
Occup Environ Med,
1994;51:589-592,
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