Occupational Asthma Reference

ChanYeung M, Mechanism of occupational asthma due to western red cedar (Thuja plicata), Am J Industr Med, 1994;25:13-18,

Keywords: oa, review, Western red cedar, red cedar, cedar, plicatic acid, IgG

Known Authors

Moira Chan-Yeung, University of Hong Kong Moira Chan-Yeung

If you would like to become a known author and have your picture displayed along with your papers then please get in touch from the contact page. Known authors can choose to receive emails when their papers receive comments.


Occupational asthma due to Western red cedar is the most common form of occupational asthma in the Pacific Northwest and affects 4-13.5% of the exposed population. It has been shown to be caused by plicatic acid, a low molecular weight compound present uniquely in the wood. The mechanism of asthma induced by plicatic acid is not known, as specific IgG antibodies were found only in about 20% of patients. Sera from patients with red cedar asthma failed to passively sensitize human lung fragments of human basophils. Basophils from patients with this disease released histamine when challenged directly with plicatic acid in a specific manner. Immunologic mechanisms other than Type I hypersensitivity reaction are likely to be involved

Full Text

Full text of this reference not available

Please Log In or Register to add the full text to this reference

Associated Questions

There are no associations for this paper.

Please Log In or Register to put forward this reference as evidence to a question.


Please sign in or register to add your thoughts.

Oasys and occupational asthma smoke logo