Changes in NSBR and FeNO in 29% of workers with a positive SIC to epoxy resins

Changes in NSBR were seen in 2/7 (29%) and FeNO in 2/7 (29%) in a case series from Helsinki and Madrid of 15 workers with a positive SIC to polyamines (unspecified) used in epoxy resin systems, and 3 powdercoaters with TGIC reactions. Of the polyamines 12/15 had late reactions and 2/15 dual reactions. Mean time from first exposure 10 years and time with symptoms 1.9 years. Many were making windmills. Work related rhinitis in about half, 2/3 TGIC positive in 2/3 TGIC reactors (No comment on whether the third kept PEF records). 13% had contact dermatitis. Air measurements of polyamines very low.

References

	Suojalehto H, Sastre J, Merimaa E, Lindström I, Suuronen K. , Occupational asthma from epoxy compounds., J Allergy Clin Immunol Pract, 2019;7:191-198,10.1016/j.jaip.2018.07.023

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