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 Home > News > Should we accept increased diurnal variation in PEF or FEV1 in place of mandatory NSBR in the diagnosis of acute irritant-induced asthma?

Should we accept increased diurnal variation in PEF or FEV1 in place of mandatory NSBR in the diagnosis of acute irritant-induced asthma?

 Should we accept increased diurnal variation in PEF or FEV1 in place of mandatory NSBR in the diagnosis of acute irritant-induced asthma?
A review of acute irritant-induced aasthma showing chlorine-related exposures remain the commonest cause, but most reports do not contain enough information to fulfill the original Brooks definition. It seems reasonable to accept increased diurnal variation in PEF or FEV1, or bronchodilator response, in place of mandatory non-specific bronchial reactivity, as this has been shown to be less frequent in neutrophilic (as opposed to eosinophilic) occupational asthma

References

Abstract Available for Updated review of reported cases of reactive airways dysfunction syndrome Walters GI, Huntley CC, Updated review of reported cases of reactive airways dysfunction syndrome, Occup Med, 2020;70:490-495,https://doi.org/10.1093/occmed/kqaa133
Gareth Walters, Heartlands, an author of 'Updated review of reported cases of reactive airways dysfunction syndrome' Chris Huntley, University Hospitals Birmingham, an author of 'Updated review of reported cases of reactive airways dysfunction syndrome'

Full Text Available for Sensitization and irritant-induced occupational asthma with latency are clinically indistinguishable Burge PS, Moore VC, Robertson AS, Sensitization and irritant-induced occupational asthma with latency are clinically indistinguishable, Occup Med, 2012;62:129-133,
Sherwood Burge, Oasys, an author of 'Sensitization and irritant-induced occupational asthma with latency are clinically indistinguishable' Vicky Moore, Oasys, an author of 'Sensitization and irritant-induced occupational asthma with latency are clinically indistinguishable' Alastair Robertson, Selly Oak Hospital, an author of 'Sensitization and irritant-induced occupational asthma with latency are clinically indistinguishable'

Full Text Available for Differentiating occupational asthmatics from non-occupational asthmatics and irritant-exposed workers Anees W, Blainey D, Moore VC, Robertson K, Burge PS, Differentiating occupational asthmatics from non-occupational asthmatics and irritant-exposed workers, Occup Med, 2011;61:191-195,
David Blainey, Essex, UK, an author of 'Differentiating occupational asthmatics from non-occupational asthmatics and irritant-exposed workers' Sherwood Burge, Oasys, an author of 'Differentiating occupational asthmatics from non-occupational asthmatics and irritant-exposed workers' Wasif Anees, Oasys, an author of 'Differentiating occupational asthmatics from non-occupational asthmatics and irritant-exposed workers' Vicky Moore, Oasys, an author of 'Differentiating occupational asthmatics from non-occupational asthmatics and irritant-exposed workers'

Full Text Available for Reactive airways dysfunction syndrome (RADS). Persistent asthma syndrome after high level irritant exposure Brooks SM, Weiss MA, Bernstein IL, Reactive airways dysfunction syndrome (RADS). Persistent asthma syndrome after high level irritant exposure, Chest, 1985;88:376-384,
Stuart Brooks, University of South Florida, an author of 'Reactive airways dysfunction syndrome (RADS). Persistent asthma syndrome after high level irritant exposure' Leonard Bernstein, Cincinatti, an author of 'Reactive airways dysfunction syndrome (RADS). Persistent asthma syndrome after high level irritant exposure'

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