Mycophenolate treatment of chronic HP less effective in patients with short telomers |
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This is an interesting observational study showing that in patients with hypersensitivity pneumonitis there is a relationship between response to mycophenolate mofetil and telomer length, with little benefit in the quartile with the shortest telomers. This obviously needs repeating in a prospective study.
References
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Adegunsoye A, Morisset J, Newton CA, Oldham JM, Vittinghoff E, Linderholm AL, Strek ME, Noth I, Garcia CK, Wolters PJ, Ley B,
Leukocyte Telomere Length and Mycophenolate Therapy in Chronic Hypersensitivity Pneumonitis,
Eur Respir J,
2020;:,10.1183/13993003.02872-2020
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