Work-exacerbated asthma. ATS statement

Work-exacerbated asthma (WEA) is defined as pre-existing or concurrent asthma that is worsened by workplace conditions Epidemiological studies conducted in general populations indicate that WEA occurs in a substantial proportion of adults with asthma, with a median prevalence estimate of 21.5%.  A wide variety of conditions at work can exacerbate asthma symptoms, including irritant chemicals, dusts, second-hand smoke, common allergens that may be present at work, as well as other “exposures” such as emotional stress, worksite temperature, and physical exertion. Patients with WEA who experience persistent work-related symptoms resemble occupational asthma (OA) cases with respect to severity of asthma and medication requirements, as well as socioeconomic factors like unemployment and loss of labour-derived income. Compared with asthma unrelated to work, WEA is associated with more symptomatic days, a greater utilization of health-care resources, and a lower quality of life. The possibility of WEA should be carefully addressed in any working patient with asthma by inquiring about the work-relatedness of his/her asthma symptoms. There is limited evidence pertaining to the natural history of WEA. Avoidance or reduction of exposure can often lead to an improvement in asthma symptoms.

References

	Henneberger PK, Redlich CA, Callahan DB, Harber P, Lemière C, Martin J, Tarlo SM, Vandenplas O, An Official American Thoracic Society Statement: Work-Exacerbated Asthma, Am J Respir Crit Care Med, 2011;184:368-378,

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