What is the sensitivity and specificity of respiratory questionnaires in the diagnosis of validated cases of occupational asthma?

The following references have been associated with this question by users of this website. They do not form part of the BOHRF occupational asthma guidelines.

burgeps Bolen 2007 The study compared real-time diary cards of current symptoms and bronchodilator use with a telephone interview after the completion of diary cards. There was a poor correlation between questions asking for asthma symptoms or or bronchodilator treatment improving away from work and the diary card assessments. Asthma symptoms reported retrospectively improving away from work sensitivity 15%; specificity 87%. Less bronchodilators on restdays sensitivity 15% and specificity 89%. Using contemporary diary card data symptoms sensitivity 62%, specificity 54%; bronchodilator usage sensitivity 62%, specificity 65%. The comparitor was serial PEF measurements showing occupational asthma.
burgeps Vandenplas 2005
Nelson Teixeira Jr American 1995
burgeps Labrecque 2011 The original screening was with questionnaire identifying 6.3% of isocyanate spray painters (n=182). Of these 103 were thought not to have OA after a medical. 79 were referred for investigation, NSBR <8mg/ml in 55/79. 20 had positive isocyanate challenges (0.69% of the original cohort).
burgeps Ellis 2018

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