What are the sensitivity and the specificity of changes in non-specific reactivity at work and away from work in the diagnosis of validated cases of occupational asthma?


** 2- Changes in non-specific reactivity at and away from work alone have only moderate sensitivity and specificity for diagnosis.

Evidence

Cote J, Kennedy S, ChanYeung M , Sensitivity And Specificity Of PC20 And Peak Expiratory Flow Rate In Cedar Asthma , J Allergy Clin Immunol , 1990 ; 85 : 592-598

Perrin B, Lagier F, L'Archeveque J, Cartier A, Boulet LP, Cote J, Malo JL , Occupational Asthma: Validity Of Monitoring Of Peak Expiratory Flow Rates And Non-Allergic Bronchial Responsiveness As Compared To Specific Inhalation Challenge , Eur Respir J , 1992 ; 5 : 40-8

Tarlo SM, Broder I , Outcome of assessment for occupational asthma , Chest , 1991 ; 100 : 329-335


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