BOHRF Original Authors' Main Conclusions
The original authors' main conclusions are taken from Abstract, Results and
Discussion. They are decided upon by the authors of the BOHRF occupational
asthma guidelines and form part of the guidelines.
344 employees exposed to flour in bakeries or mills in 7 sites were assessed by self completed questionnaire, and sensitisation measured by the response to skin prick tests, were related to intensity of exposure both to total dust and to flour aeroallergen. Among 264 previously unexposed subjects, work-related symptoms (which started after first employment at site) were related to exposure intensity, especially when exposure was expressed in terms of flour aeroallergen. The relations with eye/nose and skin symptoms were independent of atopic status and cigarette smoking. Positive skin test responses to mixed flour and to alpha amylase were also more frequent with increasing exposure intensity, although this was confounded by atopic status. There was only a weak association between symptoms and specific sensitisation.
BOHRF Associated Evidence Statements
The BOHRF occupational asthma guidelines state that this reference is associated
with the following evidence statements
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