Cockcroft A, Edwards J, McCarthy P et al, Allergy in laboratory animal workers, Lancet, 1981;1:827-828,

BOHRF Original Authors' Main Conclusions

The original authors' main conclusions are taken from Abstract, Results and Discussion. They are decided upon by the authors of the BOHRF occupational asthma guidelines and form part of the guidelines.

An association significant at the 2% level was found between skin test atopic status and asthma from animal contact. Subjects with a previous history of asthma were not significantly more likely to develop symptoms from animal contact but were more likely to develop animal-related asthma. The authors conclude that excluding atopic individuals will not solve the problem, and screening new entrants is unlikely to be successful in view of the long average exposure period before symptoms develop and the fact that skin reactivity to animal extracts is rarely present without symptoms.

Non Bohrf Information

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