Tarlo SM, Leung K, Broder Iet al, Asthmatic subjects symptomatically worse at work: prevalence and characterization among a general asthma clinic population, Chest, 2000;118:1309-1314,

BOHRF Original Authors' Main Conclusions

The original authors' main conclusions are taken from Abstract, Results and Discussion. They are decided upon by the authors of the BOHRF occupational asthma guidelines and form part of the guidelines.

Fifty-one patients reported at their initial visit that their asthma was worse at work and was not worse on weekends or holidays off work (i.e., 16% of the adult-onset employed asthmatics, 12% of all the adult-onset asthmatic subjects, and 7% of all the adult asthmatics in the clinic). A retrospective chart review of the 51 patients reporting worsened asthma at work indicated probable sensitizer-induced occupational asthma in 8 patients, based on history, exposure to a recognized respiratory sensitizer, and at least one positive objective test supporting occupational asthma. Twenty-five of the 51 asthmatic subjects whose asthma was worse at work likely had work aggravation of underlying asthma, a determination that was based on their recorded history of transient worsening at work and workplace exposure to recognized respiratory aggravating factors, but had no identified or likely workplace.

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