BOHRF Original Authors' Main Conclusions
The original authors' main conclusions are taken from Abstract, Results and
Discussion. They are decided upon by the authors of the BOHRF occupational
asthma guidelines and form part of the guidelines.
The prevalence of specific IgE was highest in the mold and intermittent groups (54%), in comparison with the coil assembly (25%) and office (0%) groups. Since ventilation was installed and tetrachlorophthalic anhydride (TCPA) exposures reduced to less than 0.1 mg/m3, there was a marked decrease in symptoms and no new cases of occupational asthma among newly hired workers at the plant. A high prevalence of respiratory symptoms was reported. After adjusting for smoking status the differences between exposure groups was not significant. Associations were found between the prevalence of TCPA-specific IgE responses and both exposure status and duration of employment. There was a higher prevalence of sensitisation among those who have never smoked and former smokers.
BOHRF Associated Evidence Statements
The BOHRF occupational asthma guidelines state that this reference is associated
with the following evidence statements
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