Occupational Asthma Reference

Cruz MJ, Costa R, Marquilles E, Morell F, Munoz X, Occupational asthma caused by chromium and nickel, Archivos de Bronconeumologia, 2006;42:302-306,

Keywords: Barcelona, Spain, Nickel, case report, nickel plater, prick test, challenge, dual reaction

Known Authors

Maria Jesus Cruz, Barcelona Maria Jesus Cruz

Xavier Munoz, Barcelona Xavier Munoz

Ferran Morell, Vall d'Hebron Hospital, Barcelona Ferran Morell

Roser Costa, Barcelona (now moved) Roser Costa

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We report the case of a 40-year-old woman who developed occupational asthma following exposure to chromium and nickel in the nickel-plating section of a metalworks company. Skin prick tests for specific antibodies proved positive for nickel chloride at a concentration of 1 mg/mL and negative for potassium dichromate. The specific bronchial provocation test confirmed the diagnosis of occupational asthma due to exposure to chromium and nickel. The patient presented a late positive reaction to nickel chloride (0.1 mg/mL) and an immediate positive reaction to a 10 mg/mL solution of potassium dichromate. These results indicate a dual response to nickel and chromium in this patient

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Also a positive immediate reaction to potassium dichromate at 10mg/ml. ? specific at this concentration

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