Occupational Asthma Reference

Leroyer C, Perfetti L, Cartier A, Malo JL, Can reactive airways dysfunction syndrome (RADS) transform into occupational asthma due to "sensitisation" to isocyanates?, Thorax, 1998;53:152-153,

Keywords: Canada, rads, oa, isocyanate, irritant, challenge

Known Authors

André Cartier, Hôpital de Sacré Coeur, Montreal, Quebec, Canada André Cartier

Jean-Luc Malo, Hôpital de Sacré Coeur, Montreal, Quebec, Canada Jean-Luc Malo

Luca Perfetti, Fondazione Salvatore Maugeri, Pavia Luca Perfetti

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The case history is described of a worker who presented with a history suggestive of reactive airways dysfunction syndrome which occurred after an acute high level inhalation of diphenylmethane diisocyanate. Further exposure at work, at a time when concentrations of isocyanates were no longer "irritant", suggested occupational asthma; this diagnosis was confirmed by a specific inhalation challenge test

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