Occupational Asthma Reference

Fishwick D, Fletcher AM, Pickering CAC, Niven RM, Faragher EB, Respiratory symptoms and dust exposure in Lancashire cotton and man-made fiber mill operatives, Am J Respir Crit Care Med, 1994;150:441-447,

Keywords: cotton, mill, byssinosis, chronic bronchitis, prevalence, am, ep, cross sectional

Known Authors

Tony Pickering, Wythenshawe Hospital, Manchester, UK Tony Pickering

David Fishwick, Royal Hallamshire Hospital, Sheffield, UK David Fishwick

Angela Fletcher, North West Lung Centre, Manchester Angela Fletcher

Rob Niven, Wythenshawe Hospital, Manchester Rob Niven

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A cross-sectional study of work-related symptoms and cotton dust exposure was made in 404 man-made fiber and 1,048 cotton operatives in Lancashire spinning mills; 39 cotton-exposed operatives (3.7%) had symptoms of byssinosis. This was associated on regression analysis with cumulative lifetime cotton dust exposure (p < 0.001), total years spent carding (p < 0.001), and currently working in the carding area (p = 0.0041). Smoking habit did not differ significantly between byssinotic and nonbyssinotic workers. Other work-related symptoms were common: chronic bronchitis (CB) and persistent cough. The prevalence of CB correlated positively with dust exposure (r = 0.59). Cotton dust sampling was performed in the work area (SDPRES) and personal breathing zone (PD1). A retrospective estimate of lifetime cotton dust exposure based on SDPRES correlated best with the prevalence of byssinosis (r = 0.797), although correlations with PD1 (r = 0.709) and SDPRES (r = 0.594) were also significant

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