Occupational Asthma Reference

Mapp CE, Isocyanates: adverse effects on health [Italian], Med Lav, 1991;82:328-335,

Keywords: isocyanate, TDI, mechanism, review

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Christina Mapp, Padova University Christina Mapp

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The paper describes the main adverse biological effects of isocyanates, particularly toluene di-isocyanate (TDI). It is not intended to be simply a review of the literature but a stimulus for further investigations on the mechanism of action, chemical characterization, environmental release, exposure, fate, health effects, carcinogenicity and mutagenicity of isocyanates

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