Occupational Asthma Reference

Dumas O, Le Moual N, Lowe AJ, Lodge CJ, Zock JP, Kromhout H, Erbas B, Perret JL, Dharmage SC, Benke G, Abramson MJ, Influence of childhood asthma and allergies on occupational exposure in early adulthood: A prospective cohort study, Int J Environ Res Public Health, 2019;19:16 (12),DOI: 10.3390/ijerph16122163

Keywords: job selection, asthma, allergy, cohort, Australia

Known Authors

Jan-Paul Zock, Municipal Institute of Medical Research, Barcelona, Spain Jan-Paul Zock

Michael Abramson, Monash University, Melbourne, Australia Michael Abramson

Orianne Dumas, Villejuif, France Orianne Dumas

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We aimed to determine whether history of asthma/allergies in childhood was associated with avoidance of jobs with exposure to asthmagens in early adulthood. The Melbourne Atopic Cohort Study recruited 620 children at high risk of allergic diseases at birth (1990-1994). Asthma, hay fever and eczema were evaluated by questionnaires during childhood. A follow-up in early adulthood (mean age: 18 years) collected information on the current job. Occupational exposure to asthmagens/irritants was evaluated using a job-exposure matrix. The association between history of asthma/allergies in childhood and working in a job with exposure to asthmagens/irritants was evaluated by logistic regression, adjusted for age, sex and parental education. Among 363 participants followed-up until early adulthood, 17% worked in a job with exposure to asthmagens/irritants. History of asthma (35%) was not associated with working in an exposed job (adjusted OR: 1.16, 95% CI: 0.65-2.09). Subjects with history of hay fever (37%) and eczema (40%) were more likely to enter exposed jobs (significant for hay fever: 1.78, 1.00-3.17; but not eczema: 1.62, 0.91-2.87). In conclusion, young adults with history of allergies were more likely to enter exposed jobs, suggesting no avoidance of potentially hazardous exposures. Improved counselling against high risk jobs may be needed for young adults with these conditions.

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