Occupational Asthma Reference

Burge PS, Reynolds J, Trotter S, Burge GA, Walters G, Histologist's original opinion compared with multidisciplinary team in determining diagnosis in interstitial lung disease, Thorax, 2017;72:280-281,org/10.1136/thoraxjnl-2016-208776

Keywords: ILD, MDT, UK

Known Authors

Sherwood Burge, Oasys Sherwood Burge

John Reynolds, Birmingham Heartlands Hospital John Reynolds

Gareth Walters, Heartlands Gareth Walters

Geraldine Burge, Birmingham Heartlands Hospital Geraldine Burge

Simon Trotter, Birmingham Heartlands Hospital Simon Trotter

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Guidelines recommend that multidisciplinary interstitial lung disease meeting (ILD MDT) decisions become the gold standard for diagnosis, replacing the histologist from this position, and identify this as requiring supportive evidence. We have compared diagnoses from lung biopsy material made by expert histologists with the subsequent consensus opinion from a properly constituted ILD MDT in 71 consecutive patients referred to a regional thoracic unit. MDT changed the original histological diagnoses in 30% (95% CI 19.3% to 41.6%) and strengthened the diagnoses from probable to confident in a further 17% (95% CI 9.1% to 27.7%). The assessment of hypersensitivity pneumonitis, non-necrotising granulomas and organising pneumonia accounted for the majority of the changes.

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