Hagmar L, Bellander T, Ranstam J, Skerfving S, Piperazine-induced airway symptoms: exposure-response relationships and selection in an occupational setting, Am J Ind Med, 1984;6:347-357,

BOHRF Original Authors' Main Conclusions

The original authors' main conclusions are taken from Abstract, Results and Discussion. They are decided upon by the authors of the BOHRF occupational asthma guidelines and form part of the guidelines.

This study showed a strong exposure-response relationship as to frequency of work-related airway symptoms indicating asthma. In the most exposed group, about a third of the workers had experienced such symptoms. There was also an association between piperazine exposure and chronic bronchitis.

BOHRF Associated Evidence Statements

The BOHRF occupational asthma guidelines state that this reference is associated with the following evidence statements

*** 2++ The risk of sensitisation and occupational asthma is increased by higher exposures to many workplace agents.

Non Bohrf Information

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