Vandenplas O, Delwiche JP Depelchin S et al, Latex Gloves With A Lower Protein Content Reduce Bronchial Reactions In Subjects With Occupational Asthma Caused By Latex, Am J Respir Crit Care Med, 1995;151:887-891,

BOHRF Original Authors' Main Conclusions

The original authors' main conclusions are taken from Abstract, Results and Discussion. They are decided upon by the authors of the BOHRF occupational asthma guidelines and form part of the guidelines.

Using inhalation challenges, the bronchial response to hypoallergenic gloves was evaluated in 8 health care workers with latex-induced asthma. Exposure to hypoallergenic gloves resulted in the absence (in 6 subjects) or a significant reduction (in 2 subjects) of bronchial response. The effects of repeated exposure to hypoallergenic gloves was assessed in 2 subjects who did not demonstrate changes in peak expiratory flow rates and non-specific bronchial responsiveness to histamine. This study on a limited number of patients suggests that the use of hypoallergenic gloves could be an effective means of reducing the risk of asthmatic reactions in health care workers with latex-induced asthma when complete avoidance cannot be achieved.

BOHRF Associated Evidence Statements

The BOHRF occupational asthma guidelines state that this reference is associated with the following evidence statements

*** 2++ The likelihood of improvement or resolution of symptoms or of preventing deterioration is greater in workers who have no further exposure to the causative agent.

Non Bohrf Information

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