Tarlo SM, Liss GM, Dias C et al, Assessment of the relationship between isocyanate exposure levels and occupational asthma, Am J Ind Med, 1997;32:517-521,

BOHRF Original Authors' Main Conclusions

The original authors' main conclusions are taken from Abstract, Results and Discussion. They are decided upon by the authors of the BOHRF occupational asthma guidelines and form part of the guidelines.

Identifies Ontario cases of isocyanate-induced occupational asthma and the companies at which they worked. Compares levels of isocyanate concentrations measured at 20 case companies with non-case companies based on air samples. Results provide some evidence that facilities having occupational asthma claims have higher isocyanate exposures than those without claims.

BOHRF Associated Evidence Statements

The BOHRF occupational asthma guidelines state that this reference is associated with the following evidence statements

*** 2++ The risk of sensitisation and occupational asthma is increased by higher exposures to many workplace agents.

*** 2++ Reducing airborne exposure reduces the number of workers who become sensitised and who develop occupational asthma.

Non Bohrf Information

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