Merget R, Kulzer R, DierkesGlobisch A et al, Exposure-effect relationship of platinum salt allergy in a catalyst production plant: conclusions from a 5-year prospective cohort study, J Allergy Clin Immunol, 2000;105:364-370,

BOHRF Original Authors' Main Conclusions

The original authors' main conclusions are taken from Abstract, Results and Discussion. They are decided upon by the authors of the BOHRF occupational asthma guidelines and form part of the guidelines.

11.3% and 2% study population developed positive platinum salts skin prick test in high and low exposure groups respectively. Development of symptoms was associated with exposure. Smoking was significant predictor of positive platinum salts skin prick test, estimated relative risk 3.9. Atopy or bronchial hyper-responsiveness were not significant predictors.

BOHRF Associated Evidence Statements

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