Lemiere C, Cartier A, Malo JL et al, Persistent specific bronchial reactivity to occupational agents in workers with normal nonspecific bronchial reactivity, Am J Respir Crit Care Med, 2000;162:976-980,

BOHRF Original Authors' Main Conclusions

The original authors' main conclusions are taken from Abstract, Results and Discussion. They are decided upon by the authors of the BOHRF occupational asthma guidelines and form part of the guidelines.

16 workers with occupational asthma caused by the high-molecular-weight-agents flour, psyllium and guar gum were re-exposed to assess their current specific bronchial reactivity (SBR) to the sensitisers (removed from exposure for a mean period of 5.7 years). Concludes that SBR to such agents persists in most cases (11/16) despite a normalisation of NSBR, and that this persistence is associated with a persistence of specific immunisation to the agent. IgE significantly decreased and at lower level at time of second challenge in those not experiencing an asthmatic reaction.

Non Bohrf Information

This page is showing the information from the BOHRF occupational asthma guidelines for this reference. To see additional information, including opinions left by users of this website please view the full reference. This page allows users to comment on the reference and suggest it as evidence for questions. These may be the existing questions from the Bohrf occupational asthma guidelines or questions that have been put forward by users of this website.

Oasys and occupational asthma smoke logo