Krakowiak A, Szulc B, Gorski P, Occupational respiratory diseases in laboratory animal workers; initial results, Int J Occup Med Environ Health, 1997;10:31-36,

BOHRF Original Authors' Main Conclusions

The original authors' main conclusions are taken from Abstract, Results and Discussion. They are decided upon by the authors of the BOHRF occupational asthma guidelines and form part of the guidelines.

Laboratory animal allergy develops within first years of exposure; atopy and smoking predispose to laboratory animal sensitisation and to a development of bronchial asthma and allergic rhinitis.

The following comments are from the editors of the BOHRF occupational asthma guidelines and form part of the guidelines.

Acute episodes of dyspnoea classified as asthma found in 8 subjects. In all cases, development of symptoms was concurrent with nasal symptoms

BOHRF Associated Evidence Statements

The BOHRF occupational asthma guidelines state that this reference is associated with the following evidence statements

** 2+ Sensitisation and occupational asthma are most likely to develop in the first years of exposure for workers exposed to enzymes, complex platinum salts, isocyanates and laboratory animal allergens.

Non Bohrf Information

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