Occupational Asthma Reference

Torrijos G, Rodriguez G, Perez V, Bartolome, Barragan P, Occupational allergic respiratory disease (rinoconjunctivitis and asthma) in a cheese factory worker, Journal of Allergy and Clinical Immunology: In Pra, 2018;6:1416-1418,

Keywords: cheese, oa, chymosin, new cause, rennet, omalizumab, cr, Spain

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Abstract

This is the first report of occupational IgE-mediated allergic respiratory disease caused by chymosin, an enzyme present in rennet used for the coagulation of milk in the production of cheese. The disease was severe and could be controlled only with omalizumab (decrease in symptoms, improvement in respiratory auscultation and spirometry), in addition to reducing exposure to the agent (use of mask) and pharmacological treatment (salmeterol/fluticasone, 500 µg/12 h and montelukast 10 mg/d).

Plain text: This is the first report of occupational IgE-mediated allergic respiratory disease caused by chymosin, an enzyme present in rennet used for the coagulation of milk in the production of cheese. The disease was severe and could be controlled only with omalizumab (decrease in symptoms, improvement in respiratory auscultation and spirometry), in addition to reducing exposure to the agent (use of mask) and pharmacological treatment (salmeterol/fluticasone, 500 ug/12 h and montelukast 10 mg/d).

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Which agents cause occupational asthma and which workers are at risk?
burgeps Positive intradermal test, no PFT

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