Genes separate fibrotic from non-fibrotic HP

Genes separate fibrotic from non-fibrotic HP
This paper suggests that a patients genes, particularly MUC5B and those related to short telomers, are the underlying reason why some patients with hypersensitivity pneumonitis develop the fibrotic variant. It implies, although is not stated, that the genes are more important than cessation of exposure to the progression to fibrosis.

References

Abstract Available for Common idiopathic pulmonary fibrosis risk variants are associated with hypersensitivity pneumonitis Furusawa H, Peljto AL, Walts AD, Cardwell J, Molyneaux PL, Lee JS, Pérez ERF, Wolters PJ, Yang IV, Schwartz DA, Common idiopathic pulmonary fibrosis risk variants are associated with hypersensitivity pneumonitis, Thorax, 2022;77:508-510,http://dx.doi.org/10.1136/thoraxjnl-2021-217693

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